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Low glutathione levels have been linked to oxidative stress which may play a role in conditions such as cardiovascular disease and inflammatory bowel disease

doi:10.2174/138920011795016872 Zamek-Gliszczynski MJ, Hoffmaster KA, Nezasa K, Tallman MN, Brouwer KL

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During mitochondrial depolarization or proteasome-dependent outer membrane rupture, Prohibitin 2 (PHB2) binds to LC3 through the LC3 interaction region domain, participating in targeted mitophagy degradation [14]