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SCFAs activate the GPR43 pathway to stimulate potassium efflux and hyperpolarization, consequently resulting in the activation of NOD-like receptor thermal protein domain associated protein 3 (NLRP3) inflammasome, which keeps the integrity of the intestinal barrier through reparation and cell survival under stress conditions (Li et al., 2024)

Not at full dose simultaneously but yes in alternation

These data revealed that the GH secretion profile of CRY/ male mice were changed with reduced GH secretion

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