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In a randomised, placebo-controlled double blinded phase 1 study of ascending single doses in healthy overweight humans, cotadutide was shown to be safe and, in common with the GLP-1 analogues, to be associated with dose-dependent gastrointestinal adverse events especially nausea and vomiting

Beyond clinical kidney benefits, CVOT and kidney outcome trials have consistently demonstrated benefits on HF outcomes, leading to dedicated HF outcome trials

Choline: Supports fat transport and liver function while helping maintain cellular integrity and brain health

(PubMed) Huang TS, Shyu YC, Chen HY, et al

Companies like Nuun sell effervescent tablets that easily dissolve in your favorite on-the-go cup with only 2 grams of added sugars