In the first week, the main goal is to help your body tolerate the medication
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See FDA boxed warning on thyroid C-cell tumors observed in rodent studies, included in the prescribing information for GLP-1 receptor agonists
GLP-1 inhibits intestinal contractions through mechanisms that may involve the central nervous system via vagal pathways or direct action on central receptors [24], as well as the enteric nervous system by modulating neurotransmission through presynaptic receptors affecting nitric oxide release [25,26]
In contrast, the control group comprised patients with obesity who did not receive a GLP-1 prescription during the study timeframe