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They work by inhibiting the DPP-4 enzyme, which is responsible for degrading incretin hormones

If the risk of hypoglycaemia is high, the same classes of agents and a dipeptidyl peptidase 4 (DPP-4) inhibitor or a peroxisome proliferator-activated receptors (PPAR-) agonist should be considered

[DOI] [PubMed] [Google Scholar] 45.Hur J, Sullivan KA, Callaghan BC, Pop-Busui R, Feldman EL

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